Tuberculosis preventive therapy: perspective from a multi-ethnic community
نویسندگان
چکیده
منابع مشابه
A community-based isoniazid preventive therapy for the prevention of childhood tuberculosis in Ethiopia
BACKGROUND Although children in contact with adults with tuberculosis (TB) should receive isoniazid (INH) preventive therapy (IPT), this is rarely implemented. OBJECTIVE To assess whether a community-based approach to provide IPT at the household level improves uptake and adherence in Ethiopia. METHODS Contacts of adults with smear-positive pulmonary TB (PTB+) were visited at home and exami...
متن کاملPolicy statement on preventive therapy against tuberculosis
Acknowledgements The Global Tuberculosis Programme (GTB) and UNAIDS acknowledge the following individuals who contributed to the writing of the report : David Cohn and Gavin Churchyard. Those individuals who participated in the meeting and gave additional constructive comments on earlier drafts include : K.
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BACKGROUND Tuberculosis is epidemic among workers in South African gold mines. We evaluated an intervention to interrupt tuberculosis transmission by means of mass screening that was linked to treatment for active disease or latent infection. METHODS In a cluster-randomized study, we designated 15 clusters with 78,744 miners as either intervention clusters (40,981 miners in 8 clusters) or con...
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Current therapy for cystic fibrosis (CF) focuses on minimizing the microbial community and the host's immune response through the aggressive use of airway clearance techniques, broad-spectrum antibiotics, and treatments that break down the pervasive endobronchial biofilm. Antibiotic selection is typically based on the susceptibility of individual microbial strains to specific antibiotics in vit...
متن کاملHepatotoxicity associated with isoniazid preventive therapy: a 7-year survey from a public health tuberculosis clinic.
CONTEXT Isoniazid preventive therapy for latent tuberculosis (TB) infection has been debated because of the risk of hepatotoxicity. The frequency of hepatotoxicity was 0.5% to 2.0% in early studies but may have changed with new criteria for diagnosis and patient selection. OBJECTIVE To determine the rate of isoniazid hepatotoxicity in patients managed according to current guidelines and pract...
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ژورنال
عنوان ژورنال: Respiratory Medicine
سال: 2000
ISSN: 0954-6111
DOI: 10.1053/rmed.1999.0877